#1 Most Shared Blemish & Acne Care · Japan's Top Acne Fighter

PAIR Acne Treatment Cream

Japan's most trusted acne solution. Medicated formula penetrates deep to cure pimples at the root — transparent finish that disappears under makeup.

PAIR Acne Treatment Cream 24g by LION

$8.49 $15.99 46% OFF

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Acne Won't Stop Coming Back?

Spot treatments that only dry the surface. Pimples that return in the same spot. Your skin needs something that works from the inside out.

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Surface Treatments Don't Cut It

Most acne products only dry out the top layer. The inflammation underneath stays, and the pimple comes right back in days.

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Redness That Won't Fade

Even after a pimple flattens, the angry red mark lingers for weeks. You need anti-inflammatory action, not just drying agents.

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Can't Wear It Under Makeup

Thick, white acne creams that pill under foundation. You need a treatment that goes invisible so you can actually live your life.

Breakouts at the Worst Times

Stress, hormones, late nights — acne doesn't care about your schedule. You need a fast-acting solution you can apply anytime.

Your Acne-Fighting Routine

Apply morning and evening after cleansing. Gentle tap until absorbed. Works for all skin types.

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Overnight Spot Treatment

Dab on active pimples before bed. The medicated formula works while you sleep — wake up to visibly flatter, calmer spots.

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Under-Makeup Daytime Use

Transparent formula disappears on skin. Apply before primer and foundation — no one will know you're treating acne underneath.

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Emergency Breakout Response

Feel a pimple forming? Apply immediately. The anti-inflammatory ingredients can stop it from fully developing when caught early.

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Travel-Size Essential

Compact 24g tube fits in any bag. Stress-related travel breakouts? You're covered wherever you go.

Why People Love This

Japan's pharmacy staple, now available on Yami.

4.8★
Average rating
from 327 reviews
#1
Most Shared in
Blemish & Acne Care
1000+
Units sold
on Yami
86%
Five-star
review rate

The Formula

Medicated formula with clinically proven active ingredients that target acne at the source.

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Ibuprofen Piconol (3%)

Anti-inflammatory active ingredient that reduces redness and swelling by targeting the inflammation inside the pore.

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Isopropyl Methylphenol (0.3%)

Antibacterial agent that kills acne-causing bacteria deep within the pore, preventing recurrence at the same spot.

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Slightly Acidic pH

Formulated close to skin's natural pH level. Gentle enough for sensitive skin without compromising effectiveness.

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Light Herbal Scent

Relaxing herbal fragrance that's subtle and pleasant. Non-sticky formula blends seamlessly into your skincare routine.

Key highlights sourced from official product listing on Yami. For the full ingredient list, refer to the product packaging.

The PAIR Experience

Four reasons this cream is Japan's acne essential.

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Root-Cause Treatment

Active ingredients penetrate into the skin to cure acne from the roots up — not just a surface-level fix.

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Invisible on Skin

Spreads evenly and becomes transparent. Wear it under makeup, to work, on dates — nobody will know.

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Anytime Application

Non-sticky formula can be applied at any time during the day, not only after cleansing in the mornings and evenings.

Visible Results Fast

Reviewers report flattened pimples in 1-2 days. Continued use accelerates the acne recovery cycle dramatically.

Pro Tips for PAIR Acne Treatment Cream 24g

Get the most out of your purchase with these practical tips

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Cleanse First

Always apply acne treatment to clean, dry skin. Residual makeup or sunscreen blocks active ingredients from reaching the blemish.

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Thin Layer Only

More product ≠ faster results. A thin, even layer is optimal. Over-application causes dryness and irritation without speeding healing.

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Sunscreen Is Mandatory

Acne treatments increase sun sensitivity. Always apply SPF 30+ during the day, even if you're mostly indoors.

Give It 4-6 Weeks

Skin cycles take about 28 days. Most acne treatments need 4-6 weeks of consistent use before you see significant improvement.

How It Compares

A side-by-side look at similar options.

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PAIR Acne Treatment Cream 24g vs LION PAIR Acne Cream (14g × 3)

This 24g tube is a single larger size. The 14g × 3 pack gives you the same total amount in three smaller tubes — more portable and longer-lasting supply. Choose based on your preference for tube size.

View LION PAIR Acne Cream (14g × 3) →
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PAIR Acne Treatment Cream 24g vs DONGA Acnon Cream

PAIR Treatment Cream is a Japanese gentle formula — works on acne and prevents new breakouts. DONGA Acnon is a Korean pharmaceutical treatment — more focused on active blemishes. PAIR for gentle care; DONGA for targeted treatment.

View DONGA Acnon Cream →

Frequently Asked Questions

Common questions about PAIR Acne Treatment Cream 24g

How do I use PAIR Acne Treatment Cream 24g for best results?
Cleanse the affected area gently, then apply a thin layer of PAIR Acne Treatment Cream 24g 1-2 times daily. Start with once daily to assess tolerance. LION products are formulated for consistent daily use. Avoid picking or squeezing blemishes during treatment.
Is PAIR Acne Treatment Cream 24g suitable for hormonal acne?
PAIR Acne Treatment Cream 24g can help with various types of acne including hormonal breakouts. However, persistent hormonal acne may require dermatologist consultation. LION acne products are designed for mild to moderate acne and work best as part of a consistent skincare routine.
Can I use acne treatment with sunscreen?
Yes — sunscreen is essential when using acne treatments, as some active ingredients can increase sun sensitivity. Apply acne treatment first, wait 5-10 minutes, then apply sunscreen. Explore our sunscreen category for Korean and Japanese options that pair well.
How long before I see improvement with PAIR Acne Treatment Cream 24g?
Most users see initial improvement within 1-2 weeks. Full results typically appear after 4-6 weeks of consistent use. If no improvement after 8 weeks, consider consulting a dermatologist. PAIR Acne Treatment Cream 24g works best with regular, uninterrupted use.

Ready to Clear Your Skin for Good?

$8.49 for 24g of Japan's #1 shared acne treatment. 46% off right now. Free shipping on orders over $49.

Buy Now — $8.49 View on Yami