#1 Most Shared Blemish & Acne Care · Japan's Top Acne Fighter

PAIR Acne Treatment Cream

Japan's most trusted acne solution. Medicated formula penetrates deep to cure pimples at the root — transparent finish that disappears under makeup.

PAIR Acne Treatment Cream 24g by LION

$8.49 $15.99 46% OFF

Buy Now — $8.49 Learn More

Acne Won't Stop Coming Back?

Spot treatments that only dry the surface. Pimples that return in the same spot. Your skin needs something that works from the inside out.

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Surface Treatments Don't Cut It

Most acne products only dry out the top layer. The inflammation underneath stays, and the pimple comes right back in days.

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Redness That Won't Fade

Even after a pimple flattens, the angry red mark lingers for weeks. You need anti-inflammatory action, not just drying agents.

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Can't Wear It Under Makeup

Thick, white acne creams that pill under foundation. You need a treatment that goes invisible so you can actually live your life.

Breakouts at the Worst Times

Stress, hormones, late nights — acne doesn't care about your schedule. You need a fast-acting solution you can apply anytime.

Your Acne-Fighting Routine

Apply morning and evening after cleansing. Gentle tap until absorbed. Works for all skin types.

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Overnight Spot Treatment

Dab on active pimples before bed. The medicated formula works while you sleep — wake up to visibly flatter, calmer spots.

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Under-Makeup Daytime Use

Transparent formula disappears on skin. Apply before primer and foundation — no one will know you're treating acne underneath.

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Emergency Breakout Response

Feel a pimple forming? Apply immediately. The anti-inflammatory ingredients can stop it from fully developing when caught early.

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Travel-Size Essential

Compact 24g tube fits in any bag. Stress-related travel breakouts? You're covered wherever you go.

The Numbers Speak

Japan's pharmacy staple, now available on Yami.

4.8★
Average rating
from 327 reviews
#1
Most Shared in
Blemish & Acne Care
1000+
Units sold
on Yami
86%
Five-star
review rate

What's Inside

Medicated formula with clinically proven active ingredients that target acne at the source.

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Ibuprofen Piconol (3%)

Anti-inflammatory active ingredient that reduces redness and swelling by targeting the inflammation inside the pore.

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Isopropyl Methylphenol (0.3%)

Antibacterial agent that kills acne-causing bacteria deep within the pore, preventing recurrence at the same spot.

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Slightly Acidic pH

Formulated close to skin's natural pH level. Gentle enough for sensitive skin without compromising effectiveness.

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Light Herbal Scent

Relaxing herbal fragrance that's subtle and pleasant. Non-sticky formula blends seamlessly into your skincare routine.

Key highlights sourced from official product listing on Yami. For the full ingredient list, refer to the product packaging.

The PAIR Experience

Four reasons this cream is Japan's acne essential.

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Root-Cause Treatment

Active ingredients penetrate into the skin to cure acne from the roots up — not just a surface-level fix.

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Invisible on Skin

Spreads evenly and becomes transparent. Wear it under makeup, to work, on dates — nobody will know.

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Anytime Application

Non-sticky formula can be applied at any time during the day, not only after cleansing in the mornings and evenings.

Visible Results Fast

Reviewers report flattened pimples in 1-2 days. Continued use accelerates the acne recovery cycle dramatically.

Ready to Clear Your Skin for Good?

$8.49 for 24g of Japan's #1 shared acne treatment. 46% off right now. Free shipping on orders over $49.

Buy Now — $8.49 View on Yami